Beilstein J. Org. Chem.2014,10, 1317–1324, doi:10.3762/bjoc.10.133
incubation with LPS (1 µg/mL, Sigma–Aldrich), compound 5 and scaffold 7 (two doses, 50 and 10 µg/mL).
DC phenotype
The DC phenotype was analyzed by flow cytometry with a 4 color EpicsXL cytometer (Beckman–Coulter), equipped with Expo 32 software. Cellsurfacemarkers were labelled with monoclonal antibodies
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Graphical Abstract
Figure 1:
Structure of GM3-ganglioside 1, GM3-lactone 2, GM3-lactone mimetic 3, and GM3-lactone mimetic conju...